Dnttip1 Gene Summary [Mouse]
Predicted to enable several functions, including enzyme activator activity; nucleosome binding activity; and protein homodimerization activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dnttip1 |
| Official Name | deoxynucleotidyltransferase, terminal, interacting protein 1 [Source:MGI Symbol;Acc:MGI:1923483] |
| Ensembl ID | ENSMUSG00000017299 |
| Bio databases IDs | |
| Aliases | deoxynucleotidyltransferase, terminal, interacting protein 1 |
| Synonyms | 6430706C13Rik, C20orf167, deoxynucleotidyltransferase terminal interacting protein 1, deoxynucleotidyltransferase, terminal, interacting protein 1, dJ447F3.4, P65, Tdif1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dnttip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonucleoprotein binding domain
- RGG domain
- binding protein
- DNTTIP1 dimerization domain
- ligand-dependent nuclear receptor
- protein homodimerization
- chromatin binding
- protein binding
- enzyme activator activity
- glutamine serine tyrosine-rich domain
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- activation in
- phagocytosis by
- co-activation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- Cytoplasm
- chromosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dnttip1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- histone deacetylase complex
- chromosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- protein homodimerization activity
- nucleosome binding