Ppy Gene Summary [Mouse]
Enables G protein-coupled receptor binding activity. Predicted to be involved in feeding behavior and neuropeptide signaling pathway. Located in cytoplasm and extracellular space. Is expressed in several structures, including gut. Orthologous to human PPY (pancreatic polypeptide). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppy |
| Official Name | pancreatic polypeptide [Source:MGI Symbol;Acc:MGI:97753] |
| Ensembl ID | ENSMUSG00000017316 |
| Bio databases IDs | |
| Aliases | pancreatic polypeptide |
| Synonyms | IGSPP, pancreatic polypeptide, PH, PNP, PP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppy often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PAH
- G-protein-coupled receptor binding
- hormone
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- Nucleus
- secretory granules
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppy gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- feeding behavior
- protein secretion
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor binding
- protein binding
- neuropeptide hormone activity
- hormone activity
- neuropeptide Y receptor binding