Cd2bp2 Gene Summary [Mouse]

Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be part of U5 snRNP. Predicted to colocalize with nuclear speck. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; immune system; and lung. Orthologous to human CD2BP2 (CD2 cytoplasmic tail binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cd2bp2
Official Name
CD2 cytoplasmic tail binding protein 2 [Source:MGI Symbol;Acc:MGI:1917483]
Ensembl ID
ENSMUSG00000042502
Bio databases IDs NCBI: 70233 Ensembl: ENSMUSG00000042502
Aliases CD2 cytoplasmic tail binding protein 2
Synonyms 1500011B02Rik, 2410024K20Rik, Cd2 (cytoplasmic tail) binding protein 2, CD2 cytoplasmic tail binding protein 2, FWP010, LIN1, PPP1R59, Snu40, U5-52K
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd2bp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GYF
  • ribonucleoprotein binding
  • protein binding

Pathways

Biological processes and signaling networks where the Cd2bp2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • bleeding
  • chronic fatigue syndrome
regulated by
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • fibrillar center
  • Nucleus
  • cytosol
  • spliceosomes
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd2bp2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • assembly of spliceosomal tri-snRNP

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nuclear speck
  • U4/U6 x U5 tri-snRNP complex
  • U5 snRNP
  • cytosol
  • fibrillar center
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • ribonucleoprotein complex binding

Gene-Specific Assays for Results You Can Trust

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