Copz2 Gene Summary [Mouse]
Predicted to be involved in intra-Golgi vesicle-mediated transport; intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in COPI-coated vesicle. Predicted to be part of COPI vesicle coat. Orthologous to human COPZ2 (COPI coat complex subunit zeta 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Copz2 |
| Official Name | coatomer protein complex, subunit zeta 2 [Source:MGI Symbol;Acc:MGI:1929008] |
| Ensembl ID | ENSMUSG00000018672 |
| Bio databases IDs | |
| Aliases | coatomer protein complex, subunit zeta 2 |
| Synonyms | 1110012D12Rik, coatomer protein complex, subunit zeta 2, coatomer protein complex, subunit ζ 2, COPI coat complex subunit zeta 2, COPI coat complex subunit ζ 2, zeta2-COP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Copz2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Clathrin adaptor complex small chain
- APS2
- Longin-like domains
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- ER-to-Golgi intermediate compartment
- cytosol
- endoplasmic reticulum membrane
- Golgi membrane
- transport vesicles
- cis Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Copz2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retrograde vesicle-mediated transport, Golgi to ER
- intra-Golgi vesicle-mediated transport
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cis-Golgi network
- cytosol
- Golgi membrane
- transport vesicle
- endoplasmic reticulum-Golgi intermediate compartment membrane
- COPI vesicle coat