Arcn1 Gene Summary [Mouse]
Acts upstream of or within several processes, including Golgi vesicle transport; adult locomotory behavior; and cerebellar Purkinje cell layer maturation. Located in COPI-coated vesicle; Golgi apparatus; and endoplasmic reticulum. Is expressed in several structures, including genitourinary system. Orthologous to human ARCN1 (archain 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Arcn1 |
| Official Name | archain 1 [Source:MGI Symbol;Acc:MGI:2387591] |
| Ensembl ID | ENSMUSG00000032096 |
| Bio databases IDs | |
| Aliases | archain 1 |
| Synonyms | 4632432M07Rik, ARCHAIN 1, COPD, delta-COP, nur17, SRMMD, SSMG, δ-COP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arcn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AP_MHD_Cterm
- Adaptor complexes medium subunit family
- protein binding
- Longin-like domains
Pathways
Biological processes and signaling networks where the Arcn1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- atopic dermatitis
- idiopathic membranous nephropathy
- rhizomelic short stature with microcephaly, micrognathia, and developmental delay
- rheumatoid arthritis
- hereditary disorder
- non-small cell lung cancer
- infection by lymphocytic choriomeningitis virus
- infection by Human parainfluenza virus 3
- infection by vesicular stomatitis virus
role in cell
- transport
- cell death
- production in
- cell viability
- activation in
- expression in
- phosphorylation in
- replication in
- growth
- growth in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Endoplasmic Reticulum
- cytosol
- endoplasmic reticulum membrane
- Golgi membrane
- transport vesicles
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Arcn1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cerebellar Purkinje cell layer maturation
- ER to Golgi vesicle-mediated transport
- retrograde vesicle-mediated transport, Golgi to ER
- pigmentation
- adult locomotory behavior
- intracellular protein transport
- Golgi localization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- cytosol
- Golgi membrane
- transport vesicle
- COPI vesicle coat
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding