Ndel1

Enables identical protein binding activity and tubulin binding activity. Involved in several processes, including insulin receptor signaling pathway; lysosome localization; and regulation of plasma membrane bounded cell projection organization. Acts upstream of or within several processes, including cytoskeleton organization; generation of neurons; and transport along microtubule. Located in several cellular components, including axon hillock; cytoskeleton; and synaptic vesicle. Part of microtubule associated complex. Is expressed in several structures, including central nervous system; craniocervical region bone; integumental system; metanephros; and sensory organ. Orthologous to human NDEL1 (nudE neurodevelopment protein 1 like 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ndel1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ndel1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ndel1 gene, providing context for its role in the cell.