Ccl9 Gene Summary [Mouse]

Predicted to enable CCR1 chemokine receptor binding activity; chemoattractant activity; and chemokine activity. Acts upstream of or within negative regulation of myoblast differentiation. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and limb. Orthologous to human CCL15 (C-C motif chemokine ligand 15) and CCL23 (C-C motif chemokine ligand 23). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ccl9
Official Name
chemokine (C-C motif) ligand 9 [Source:MGI Symbol;Acc:MGI:104533]
Ensembl ID
ENSMUSG00000019122
Bio databases IDs NCBI: 20308 Ensembl: ENSMUSG00000019122
Aliases chemokine (C-C motif) ligand 9
Synonyms CCF18, Ccl10, Ccl9/10, C-C motif chemokine ligand 9, MIP-1 gamma, MIP-1 γ, MRP-2, Scya10, Scya9
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccl9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CCR chemokine receptor binding
  • chemokine
  • chemoattractant
  • Small cytokines (intecrine/chemokine), interleukin-8 like
  • cytokine

Pathways

Biological processes and signaling networks where the Ccl9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • rheumatoid arthritis
  • insulin-dependent diabetes mellitus
  • metastasis
  • Sjögren syndrome
  • plasma cell neoplasm
  • B cell cancer
  • mature B-cell neoplasia
regulated by
regulates
  • Ca2+
  • NFkB (complex)
  • CCR1
role in cell
  • apoptosis
  • activation
  • differentiation
  • migration
  • survival
  • chemotaxis
  • quantity
  • internalization by
  • leukemic potential
  • recruitment

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cell surface
  • intracellular space

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.