Timm9 Gene Summary [Mouse]

Predicted to enable membrane insertase activity; protein homodimerization activity; and protein-folding chaperone binding activity. Involved in protein insertion into mitochondrial inner membrane. Located in mitochondrion. Part of mitochondrial intermembrane space protein transporter complex. Is expressed in genitourinary system; orbito-sphenoid; otic capsule; and telencephalon ventricular layer. Orthologous to human TIMM9 (translocase of inner mitochondrial membrane 9). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Timm9
Official Name
translocase of inner mitochondrial membrane 9 [Source:MGI Symbol;Acc:MGI:1353436]
Ensembl ID
ENSMUSG00000021079
Bio databases IDs NCBI: 30056 Ensembl: ENSMUSG00000021079
Aliases translocase of inner mitochondrial membrane 9
Synonyms 2810011L15Rik, Tim10a, TIM9, TIM9A, Timm10, Timm9a, translocase of inner mitochondrial membrane 9
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Timm9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc ion binding
  • protein homodimerization
  • Tim10/DDP family zinc finger
  • protein binding
  • chaperone binding
  • transporter

Pathways

Biological processes and signaling networks where the Timm9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • Sengers syndrome
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • inner membrane
  • Mitochondria
  • mitochondrial intermembrane space
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Timm9 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein targeting to mitochondrion
  • sensory perception of sound
  • protein import into mitochondrial inner membrane

Cellular Component

Where in the cell the gene product is active
  • mitochondrial intermembrane space
  • mitochondrial intermembrane space protein transporter complex
  • mitochondrion
  • mitochondrial inner membrane
  • mitochondrial inner membrane protein insertion complex

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • membrane insertase activity
  • protein binding
  • protein homodimerization activity
  • chaperone binding

Gene-Specific Assays for Results You Can Trust

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