Stmn4 Gene Summary [Mouse]

Predicted to enable tubulin binding activity. Predicted to be involved in microtubule depolymerization; neuron projection development; and regulation of microtubule polymerization or depolymerization. Predicted to be located in Golgi apparatus and growth cone. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; sensory organ; and skeleton. Orthologous to human STMN4 (stathmin 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Stmn4
Official Name
stathmin-like 4 [Source:MGI Symbol;Acc:MGI:1931224]
Ensembl ID
ENSMUSG00000022044
Bio databases IDs NCBI: 56471 Ensembl: ENSMUSG00000022044
Aliases stathmin-like 4
Synonyms Lagl, LAGLS1, RB3, stathmin 4, stathmin-like 4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Stmn4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tubulin binding domain
  • membrane attachment signal
  • protein binding
  • stathmin domain
  • Stathmin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • vertigo
regulated by
regulates
  • tubulin
  • guanosine triphosphate
role in cell
  • depolymerization
  • elongation
  • destabilization
  • catastrophe
  • rescue

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Stmn4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron projection development
  • regulation of microtubule polymerization or depolymerization
  • microtubule depolymerization

Cellular Component

Where in the cell the gene product is active
  • growth cone
  • cytoplasm
  • Golgi apparatus
  • neuron projection

Molecular Function

What the gene product does at the molecular level
  • tubulin binding

Gene-Specific Assays for Results You Can Trust

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