STMN4 Gene Summary [Human]
Predicted to enable tubulin binding activity. Predicted to be involved in microtubule depolymerization; neuron projection development; and regulation of microtubule polymerization or depolymerization. Predicted to be located in Golgi apparatus and growth cone. Predicted to be active in cytoplasm and neuron projection. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | STMN4 |
| Official Name | stathmin 4 [Source:HGNC Symbol;Acc:HGNC:16078] |
| Ensembl ID | ENSG00000015592 |
| Bio databases IDs | |
| Aliases | stathmin 4 |
| Synonyms | Lagl, LAGLS1, RB3, stathmin 4, stathmin-like 4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STMN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tubulin binding domain
- membrane attachment signal
- protein binding
- stathmin domain
- Stathmin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STMN4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuron projection development
- regulation of microtubule polymerization or depolymerization
- microtubule depolymerization
Cellular Component
Where in the cell the gene product is active
- growth cone
- cytoplasm
- Golgi apparatus
- neuron projection
Molecular Function
What the gene product does at the molecular level
- tubulin binding