Rprd1a Gene Summary [Mouse]
Predicted to enable RNA polymerase II complex binding activity and identical protein binding activity. Predicted to be involved in RNA polymerase II promoter clearance and mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of transcription preinitiation complex. Is expressed in dorsal root ganglion; renal calyx; and submandibular gland primordium. Orthologous to human RPRD1A (regulation of nuclear pre-mRNA domain containing 1A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rprd1a |
| Official Name | regulation of nuclear pre-mRNA domain containing 1A [Source:MGI Symbol;Acc:MGI:2385066] |
| Ensembl ID | ENSMUSG00000040446 |
| Bio databases IDs | |
| Aliases | regulation of nuclear pre-mRNA domain containing 1A |
| Synonyms | BC021395, C77387, HsT3101, LOC105372067, mKIAA4077, P15RS, regulation of nuclear pre-mRNA domain containing 1A, RGD1307374 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rprd1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- VHS, ENTH and ANTH domain superfamily
- CID domain
- protein binding
- Cell-cycle alteration and expression-elevated protein in tumour
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rprd1a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- promoter clearance from RNA polymerase II promoter
- mRNA 3'-end processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA polymerase II core binding