Psmg1 Gene Summary [Mouse]
Enables proteasome binding activity. Acts upstream of or within cerebellar granule cell precursor proliferation and proteasome core complex assembly. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human PSMG1 (proteasome assembly chaperone 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Psmg1 |
| Official Name | proteasome (prosome, macropain) assembly chaperone 1 [Source:MGI Symbol;Acc:MGI:1860263] |
| Ensembl ID | ENSMUSG00000022913 |
| Bio databases IDs | |
| Aliases | proteasome (prosome, macropain) assembly chaperone 1 |
| Synonyms | C21LRP, DSCR2, Leucine rich, LRPC21, PAC-1, Pba1, proteasome assembly chaperone 1, proteasome (prosome, macropain) assembly chaperone 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Psmg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Proteasome assembly chaperone 4
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- Golgi Apparatus
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Psmg1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chaperone-mediated protein complex assembly
- cerebellar granule cell precursor proliferation
- proteasome core complex assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- Golgi apparatus
- endoplasmic reticulum
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- proteasome binding
- binding, bridging