Myom1 Gene Summary [Mouse]
Enables protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of protein secretion; protein kinase A signaling; and sarcomere organization. Predicted to act upstream of or within muscle contraction. Located in M band. Is expressed in several structures, including alimentary system; cardiovascular system; musculature; respiratory system; and skeleton. Orthologous to human MYOM1 (myomesin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Myom1 |
| Official Name | myomesin 1 [Source:MGI Symbol;Acc:MGI:1341430] |
| Ensembl ID | ENSMUSG00000024049 |
| Bio databases IDs | |
| Aliases | myomesin 1 |
| Synonyms | D430047A17Rik, Eh-Myomesin, myomesin 1, SKELEMIN |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Myom1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C2-like domain
- structural constituent of muscle
- kinase binding
- structural constituent of cytoskeleton
- FN3
- immunoglobulin domain
- Immunoglobulin like
- protein homodimerization
- Immunoglobulin I-set domain
- Fibronectin type 3 domain
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- idiopathic scoliosis
- major depression
- idiopathic hydrops fetalis
- dilated cardiomyopathy
- hypertrophic cardiomyopathy
role in cell
- morphology
- assembly
- hypertrophy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoskeleton
- myofilaments
- sarcomere
- nuclear envelope
- m-bands
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Myom1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of gene expression
- protein kinase A signaling cascade
- sarcomere organization
- extraocular skeletal muscle development
- positive regulation of protein secretion
Cellular Component
Where in the cell the gene product is active
- M band
- striated muscle myosin thick filament
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein homodimerization activity
- protein binding
- structural constituent of muscle
- kinase binding