Esco1

Predicted to enable identical protein binding activity; protein-lysine-acetyltransferase activity; and zinc ion binding activity. Predicted to be involved in mitotic sister chromatid cohesion; protein acetylation; and regulation of DNA replication. Predicted to be located in chromosome. Predicted to be active in chromatin and nucleus. Is expressed in cerebral cortex ventricular layer; gonad; reproductive system; and urinary system. Orthologous to human ESCO1 (establishment of sister chromatid cohesion N-acetyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Esco1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Esco1 gene, providing context for its role in the cell.