Atp23 Gene Summary [Mouse]
Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing and mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in several cellular components, including cell junction; cytosol; and plasma membrane. Is expressed in several structures, including cerebral cortex; heart; liver; lung; and spleen. Orthologous to human ATP23 (ATP23 metallopeptidase and ATP synthase assembly factor homolog). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp23 |
| Official Name | ATP23 metallopeptidase and ATP synthase assembly factor homolog [Source:MGI Symbol;Acc:MGI:1916984] |
| Ensembl ID | ENSMUSG00000025436 |
| Bio databases IDs | |
| Aliases | ATP23 metallopeptidase and ATP synthase assembly factor homolog |
| Synonyms | 1110068E08Rik, 2410012H02Rik, ATP23 metallopeptidase and ATP synthase assembly factor homolog, KUB3, XRCC6BP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- DNA-dependent protein kinase
- Peptidase M76 family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell junction
- intracellular membrane-bounded organelle
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial proton-transporting ATP synthase complex assembly
- mitochondrial protein processing
- double-strand break repair via nonhomologous end joining
Cellular Component
Where in the cell the gene product is active
- DNA-dependent protein kinase-DNA ligase 4 complex
- intracellular membrane-bounded organelle
- mitochondrion
- cytosol
- cell junction
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- DNA-dependent protein kinase activity
- protein binding
- metal ion binding
- metalloendopeptidase activity