Lypd1 Gene Summary [Mouse]
Enables acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Acts upstream of or within several processes, including behavioral fear response; negative regulation of protein localization to plasma membrane; and synaptic signaling. Located in membrane. Is expressed in several structures, including alimentary system; branchial arch; limb; nervous system; and sensory organ. Orthologous to human LYPD1 (LY6/PLAUR domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lypd1 |
| Official Name | Ly6/Plaur domain containing 1 [Source:MGI Symbol;Acc:MGI:1919835] |
| Ensembl ID | ENSMUSG00000026344 |
| Bio databases IDs | |
| Aliases | Ly6/Plaur domain containing 1 |
| Synonyms | 2700050C12Rik, C530008O16Rik, LY6/PLAUR domain containing 1, Lynx2, LYPDC1, PHTS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lypd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- acetylcholine receptor inhibitor
- protein binding
- receptor binding
- TFP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lypd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- synaptic transmission, cholinergic
- response to nicotine
- protein localization in plasma membrane
- behavioral fear response
Cellular Component
Where in the cell the gene product is active
- synapse
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- acetylcholine receptor binding
- acetylcholine receptor inhibitor activity