Baz2b Gene Summary [Mouse]
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be located in nucleus. Predicted to be active in chromatin. Is expressed in several structures, including central nervous system; dorsal root ganglion; forelimb bud; genitourinary system; and sensory organ. Orthologous to human BAZ2B (bromodomain adjacent to zinc finger domain 2B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Baz2b |
| Official Name | bromodomain adjacent to zinc finger domain, 2B [Source:MGI Symbol;Acc:MGI:2442782] |
| Ensembl ID | ENSMUSG00000026987 |
| Bio databases IDs | |
| Aliases | bromodomain adjacent to zinc finger domain, 2B |
| Synonyms | 5830435C13RIK, AC0099613, bromodomain adjacent to zinc finger domain 2B, bromodomain adjacent to zinc finger domain, 2B, D2Ertd794e, WALp4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Baz2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Flagellar FliJ protein
- Coiled-coil domain-containing protein 3
- PHD zinc finger
- Arginine and glutamate-rich 1
- Ciliary protein causing Leber congenital amaurosis disease
- UDM1_RNF168_RNF169-like
- F-type ATP synthase, membrane subunit b
- WSTF, HB1, Itc1p, MBD9 motif 1
- Bromodomain
- Type III secretion protein YscO
- Chromatin assembly factor 1 complex p150 subunit, N-terminal
- ClassIIa_HDAC_Gln-rich-N
- Glutamine rich N terminal domain of histone deacetylase 4
- MBD
- Growth arrest and DNA-damage-inducible proteins-interacting protein 1
- polo kinase kinase
- Domain of unknown function (DUF4515)
- RNase Y N-terminal region
- Ezrin/radixin/moesin, alpha-helical domain
- PspA/IM30 family
- DDT domain
- protein binding
- Domain of unknown function (DUF4659)
- flagellar export protein FliJ
- MAP7 (E-MAP-115) family
- Trichohyalin-plectin-homology domain
- Bivalent Mical/EHBP Rab binding domain
- PHD finger superfamily
- Domain of unknown function (DUF4200)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- neurodevelopmental disorder
- COVID-19
- dysphagia
- restless legs syndrome
- complex neurodevelopmental disorder
- sudden cardiac arrest
- single major depressive episode
role in cell
- remodeling
- remodeling in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Baz2b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding