Cstf3 Gene Summary [Mouse]
Predicted to enable mRNA binding activity. Predicted to be involved in co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage stimulating factor complex. Predicted to be active in nucleus. Is expressed in several structures, including ganglia; liver; submandibular gland primordium; thymus primordium; and vibrissa. Orthologous to human CSTF3 (cleavage stimulation factor subunit 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cstf3 |
| Official Name | cleavage stimulation factor, 3' pre-RNA, subunit 3 [Source:MGI Symbol;Acc:MGI:1351825] |
| Ensembl ID | ENSMUSG00000027176 |
| Bio databases IDs | |
| Aliases | cleavage stimulation factor, 3' pre-RNA, subunit 3 |
| Synonyms | 4732468G05Rik, cleavage stimulation factor, 3' pre-RNA, subunit 3, cleavage stimulation factor subunit 3, CSTF-77 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cstf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HAT (Half-A-TPR) repeats
- Mad3/BUB1 homology region 1
- Suppressor of forked protein (Suf)
- hinge domain
- protein binding
- proline rich domain
Pathways
Biological processes and signaling networks where the Cstf3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cstf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA 3'-end processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- mRNA cleavage stimulating factor complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- mRNA binding