Fam110a Gene Summary [Mouse]
Predicted to be involved in mitotic spindle organization. Located in several cellular components, including cell cortex; cytosol; and microtubule cytoskeleton. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; midbrain mantle layer; and telencephalon mantle layer. Orthologous to human FAM110A (family with sequence similarity 110 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam110a |
| Official Name | family with sequence similarity 110, member A [Source:MGI Symbol;Acc:MGI:1921097] |
| Ensembl ID | ENSMUSG00000027459 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 110, member A |
| Synonyms | 1700008J10Rik, 5430432M24Rik, bA371L19.3, C20orf55, F10, family with sequence similarity 110 member A, family with sequence similarity 110, member A, RGD1308904 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam110a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Centrosome-associated N terminus
- protein binding
- Centrosome-associated C terminus
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell cortex
- Nucleus
- centrosome
- cytosol
- spindle pole
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam110a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitotic spindle organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- spindle microtubule
- centrosome
- cell cortex
- spindle pole
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding