Abcf2 Gene Summary [Mouse]

Predicted to enable ATP binding activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to several human genes including ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Abcf2
Official Name
ATP-binding cassette, sub-family F (GCN20), member 2 [Source:MGI Symbol;Acc:MGI:1351657]
Ensembl ID
ENSMUSG00000028953
Bio databases IDs NCBI: 27407 Ensembl: ENSMUSG00000028953
Aliases ATP-binding cassette, sub-family F (GCN20), member 2
Synonyms 0710005O05Rik, ABC28, Abcf2 predicted, ATP binding cassette subfamily F member 2, ATP-binding cassette, sub-family F member 2, DRR3, E430001O06, EST133090, HUSSY-18
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abcf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FeS assembly ATPase SufC
  • proposed F420-0 ABC transporter, ATP-binding protein
  • ATP-binding cassette protein, ChvD family
  • methyl coenzyme M reductase system, component A2
  • protein binding
  • phosphonate C-P lyase system protein PhnL
  • nickel import ATP-binding protein NikE
  • ABC transporter
  • heme ABC exporter, ATP-binding protein CcmA
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • preeclampsia
  • obesity
regulated by
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Abcf2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.