ABCF2 Gene Summary [Human]
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Mar 2019]
Details
| Type | Protein Coding |
| Official Symbol | ABCF2 |
| Official Name | ATP binding cassette subfamily F member 2 [Source:HGNC Symbol;Acc:HGNC:71] |
| Ensembl ID | ENSG00000033050 |
| Bio databases IDs | |
| Aliases | ATP binding cassette subfamily F member 2 |
| Synonyms | 0710005O05Rik, ABC28, Abcf2 predicted, ATP binding cassette subfamily F member 2, ATP-binding cassette, sub-family F member 2, DRR3, E430001O06, EST133090, HUSSY-18 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ABCF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FeS assembly ATPase SufC
- proposed F420-0 ABC transporter, ATP-binding protein
- ATP-binding cassette protein, ChvD family
- methyl coenzyme M reductase system, component A2
- protein binding
- phosphonate C-P lyase system protein PhnL
- nickel import ATP-binding protein NikE
- ABC transporter
- heme ABC exporter, ATP-binding protein CcmA
- P-loop containing Nucleoside Triphosphate Hydrolases
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ABCF2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding