Pop7 Gene Summary [Mouse]
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Predicted to be active in nucleus. Orthologous to human POP7 (POP7 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pop7 |
| Official Name | processing of precursor 7, ribonuclease P family, (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1921347] |
| Ensembl ID | ENSMUSG00000029715 |
| Bio databases IDs | |
| Aliases | processing of precursor 7, ribonuclease P family, (S. cerevisiae) |
| Synonyms | 0610037N12Rik, POP7 homolog, ribonuclease P/MRP subunit, processing of precursor 7, ribonuclease P family, (S. cerevisiae), RPP2, RPP20 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pop7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonuclease P
- enzyme
- protein binding
- Alba
- RNA binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pop7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA processing
- rRNA processing
- tRNA 5'-leader removal
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- ribonuclease MRP complex
- intracellular membrane-bounded organelle
- multimeric ribonuclease P complex
- nucleolus
- nucleolar ribonuclease P complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ribonuclease P activity
- RNA binding
- protein binding
- ribonuclease P RNA binding