Cand2 Gene Summary [Mouse]
Enables TBP-class protein binding activity. Predicted to be involved in SCF complex assembly and protein ubiquitination. Located in nucleus. Is expressed in several structures, including limb bud; musculature; and nervous system. Orthologous to human CAND2 (cullin associated and neddylation dissociated 2 (putative)). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cand2 |
| Official Name | cullin-associated and neddylation-dissociated 2 (putative) [Source:MGI Symbol;Acc:MGI:1914338] |
| Ensembl ID | ENSMUSG00000030319 |
| Bio databases IDs | |
| Aliases | cullin-associated and neddylation-dissociated 2 (putative) |
| Synonyms | 2210404G23Rik, cullin-associated and neddylation-dissociated 2 (putative), mKIAA0667, TIP120B, Tp120b |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cand2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- HEAT-like repeat
- TATA-binding protein interacting (TIP20)
- protein binding
- HEAT repeats
- TATA-binding protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cand2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- SCF complex assembly
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- TBP-class protein binding