Nfatc2ip Gene Summary [Mouse]
Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in early embryo; eye; genitourinary system; and limb. Orthologous to human NFATC2IP (nuclear factor of activated T cells 2 interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nfatc2ip |
| Official Name | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein [Source:MGI Symbol;Acc:MGI:1329015] |
| Ensembl ID | ENSMUSG00000030722 |
| Bio databases IDs | |
| Aliases | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein |
| Synonyms | D7Ertd304e, ESC2, FLJ14639, NIP45, nuclear factor of activated T-cells 2 interacting protein, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein, RAD60 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nfatc2ip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubl1_cv_Nsp3_N-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection by parasite
role in cell
- number
- abnormal morphology
- function
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nfatc2ip gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein sumoylation
- cytokine production
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm