Zfp185 Gene Summary [Mouse]
Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm; cytoskeleton; and focal adhesion. Is expressed in several structures, including central nervous system; connective tissue; genitourinary system; hemolymphoid system gland; and limb. Orthologous to human ZNF185 (zinc finger protein 185 with LIM domain). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp185 |
| Official Name | zinc finger protein 185 [Source:MGI Symbol;Acc:MGI:108095] |
| Ensembl ID | ENSMUSG00000031351 |
| Bio databases IDs | |
| Aliases | zinc finger protein 185 |
| Synonyms | P1, SCELL, Zfp185, zinc finger protein 185, zinc finger protein 185 with LIM domain |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp185 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- LIM is a small protein-protein interaction domain, containing two zinc fingers
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- head and neck squamous cell carcinoma
- head and neck squamous cell cancer
- squamous cell cancer
- age-related hearing loss
- squamous-cell carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp185 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- focal adhesion
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding