Rbp2 Gene Summary [Mouse]
Enables lipid binding activity and molecular carrier activity. Involved in retinoid metabolic process. Acts upstream of or within triglyceride biosynthetic process. Is active in cytosol. Is expressed in embryo; intestine; lower jaw tooth; and tooth. Orthologous to human RBP2 (retinol binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rbp2 |
| Official Name | retinol binding protein 2, cellular [Source:MGI Symbol;Acc:MGI:97877] |
| Ensembl ID | ENSMUSG00000032454 |
| Bio databases IDs | |
| Aliases | retinol binding protein 2, cellular |
| Synonyms | CELLULAR RETINOL-binding protein type II, CRABP-II, CRBP2, CRBPII, Creb2, RBPC2, retinol binding protein 2, retinol binding protein 2, cellular |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid binding
- binding protein
- lipocalin/cytosolic fatty acid-binding protein family
- retinol binding
- protein binding activity, bridging
- retinoid binding
- Lipocalin / cytosolic fatty-acid binding protein family
- transporter
Pathways
Biological processes and signaling networks where the Rbp2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- colorectal cancer
regulated by
- lipopolysaccharide
- CD666
- tamibarotene
- alitretinoin
- arachidonic acid
- PP1C
- tretinoin
- okadaic acid
- tetradecanoylphorbol acetate
- RNF8
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid transport
- epidermis development
- vitamin A metabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- fatty acid binding
- retinal binding
- retinol binding
- retinoid binding