Slc66a2 Gene Summary [Mouse]
Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in membrane. Predicted to be active in endosome and trans-Golgi network. Is expressed in cerebral cortex; ganglia; liver; lung; and submandibular gland primordium. Orthologous to human SLC66A2 (solute carrier family 66 member 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc66a2 |
| Official Name | solute carrier family 66 member 2 [Source:MGI Symbol;Acc:MGI:1914193] |
| Ensembl ID | ENSMUSG00000034006 |
| Bio databases IDs | |
| Aliases | solute carrier family 66 member 2 |
| Synonyms | 2310009N05RIK, 4933425L21Rik, 5730564E11Rik, PQLC1, solute carrier family 66 member 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc66a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sugar efflux transporter for intercellular exchange
- protein binding
- PQ loop repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc66a2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid translocation
- retrograde transport, endosome to Golgi
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- endosome
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding