Nipsnap1 Gene Summary [Mouse]
Predicted to enable protein-macromolecule adaptor activity. Involved in mitophagy and sensory perception of pain. Located in membrane and mitochondrion. Is active in synaptic membrane. Is expressed in several structures, including gonad; gut; nervous system; submandibular gland primordium; and tooth. Orthologous to human NIPSNAP1 (nipsnap homolog 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nipsnap1 |
| Official Name | nipsnap homolog 1 [Source:MGI Symbol;Acc:MGI:1278344] |
| Ensembl ID | ENSMUSG00000034285 |
| Bio databases IDs | |
| Aliases | nipsnap homolog 1 |
| Synonyms | 4-Nitrophenylphosphatase domain and non-neuronal snap25-like, nipsnap homolog 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nipsnap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- enzyme
- protein binding
- NIPSNAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- synaptic membrane
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nipsnap1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of pain
- macromitophagy
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- synaptic membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding, bridging