NIPSNAP1 Gene Summary [Human]
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Details
| Type | Protein Coding |
| Official Symbol | NIPSNAP1 |
| Official Name | nipsnap homolog 1 [Source:HGNC Symbol;Acc:HGNC:7827] |
| Ensembl ID | ENSG00000184117 |
| Bio databases IDs | |
| Aliases | nipsnap homolog 1, 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1 |
| Synonyms | 4-Nitrophenylphosphatase domain and non-neuronal snap25-like, nipsnap homolog 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NIPSNAP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- enzyme
- protein binding
- NIPSNAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Mitochondria
- synaptic membrane
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NIPSNAP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of pain
- macromitophagy
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- synaptic membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding, bridging