Ly6d Gene Summary [Mouse]
Involved in lymphocyte differentiation and response to stilbenoid. Located in cell surface. Is expressed in adrenal gland; alimentary system; naris; ureter; and vibrissa. Orthologous to human LY6D (lymphocyte antigen 6 family member D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ly6d |
| Official Name | lymphocyte antigen 6 complex, locus D [Source:MGI Symbol;Acc:MGI:96881] |
| Ensembl ID | ENSMUSG00000034634 |
| Bio databases IDs | |
| Aliases | lymphocyte antigen 6 complex, locus D |
| Synonyms | E48, Ly-61, lymphocyte antigen 6 family member D, Thb |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ly6d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- TFP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- mature B-cell neoplasia
- plasma cell neoplasm
- B cell cancer
- tinea pedis
- insulin-dependent diabetes mellitus
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- infection by HIV-1
role in cell
- expression in
- migration
- cell rolling
- cisplatin resistance
- cisplatin sensitivity
- 5-fluorouracil resistance
- paclitaxel sensitivity
- 5-fluorouracil sensitivity
- paclitaxel resistance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- detergent-insoluble membrane fraction
- cell surface
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ly6d gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lymphocyte differentiation
- cell adhesion
- response to stilbenoid
Cellular Component
Where in the cell the gene product is active
- membrane
- extracellular region
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding