Rbm17 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Located in nucleus. Part of protein-containing complex. Is expressed in brain; cerebral cortex; hippocampus; ovary; and primary sex cord. Orthologous to human RBM17 (RNA binding motif protein 17). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rbm17 |
| Official Name | RNA binding motif protein 17 [Source:MGI Symbol;Acc:MGI:1924188] |
| Ensembl ID | ENSMUSG00000037197 |
| Bio databases IDs | |
| Aliases | RNA binding motif protein 17 |
| Synonyms | 2700027J02RIK, 45 kDa splicing factor, RNA binding motif protein 17, SPF45 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbm17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- G-patch domain
- RNA recognition motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- gastric adenocarcinoma
- gastric epithelial cancer
- vitiligo vulgaris
- infection by HIV-1
role in cell
- expression in
- proliferation
- apoptosis
- cell death
- reverse transcription
- quantity
- alternative splicing by
- adhesion
- reverse transcription in
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbm17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA cis splicing, via spliceosome
- alternative nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding