Syn1

Enables identical protein binding activity and protein kinase binding activity. Involved in regulation of synaptic vesicle cycle and synaptic vesicle cycle. Acts upstream of or within neurotransmitter secretion. Located in several cellular components, including postsynaptic density; synaptic vesicle membrane; and synaptonemal complex. Is active in several cellular components, including Schaffer collateral - CA1 synapse; cell body; and dendrite. Is expressed in several structures, including intercostal muscle; molar; nervous system; oocyte; and sensory organ. Used to study autism spectrum disorder and epilepsy. Human ortholog(s) of this gene implicated in X-linked epilepsy with variable learning disabilities and behavior disorders and non-syndromic X-linked intellectual disability 50. Orthologous to human SYN1 (synapsin I). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syn1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Syn1 gene, providing context for its role in the cell.