Tbc1d17 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in autophagosome and recycling endosome. Predicted to be active in cytosol. Is expressed in central nervous system and retina. Orthologous to human TBC1D17 (TBC1 domain family member 17). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tbc1d17 |
| Official Name | TBC1 domain family, member 17 [Source:MGI Symbol;Acc:MGI:2449973] |
| Ensembl ID | ENSMUSG00000038520 |
| Bio databases IDs | |
| Aliases | TBC1 domain family, member 17 |
| Synonyms | BC017607, TBC1 domain family member 17, TBC1 domain family, member 17 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tbc1d17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab-GTPase-TBC domain
- Rab-binding domain (RBD)
- Domain in Tre-2, BUB2p, and Cdc16p
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- recycling endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tbc1d17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- protein transport
- retrograde transport, endosome to Golgi
Cellular Component
Where in the cell the gene product is active
- cytosol
- recycling endosome
- autophagic vacuole
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase activator activity