Slc25a31 Gene Summary [Mouse]

Predicted to enable ATP:ADP antiporter activity. Involved in male meiosis I; regulation of mitochondrial membrane permeability; and spermatogenesis. Located in mitochondrial inner membrane. Part of mitochondrial permeability transition pore complex. Is expressed in genitourinary system; lung; pituitary gland; and vertebral axis musculature. Orthologous to human SLC25A31 (solute carrier family 25 member 31). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc25a31
Official Name
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 [Source:MGI Symbol;Acc:MGI:1920583]
Ensembl ID
ENSMUSG00000069041
Bio databases IDs NCBI: 73333 Ensembl: ENSMUSG00000069041
Aliases solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
Synonyms 1700034J06Rik, AAC4, ANT 4, LOC100364813, LOC684507, Sfec, SFEC35kDa, solute carrier family 25 member 31, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc25a31 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitochondrial carrier protein
  • protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • 16:0-16:0-16:0-16:0 cardiolipin
role in cell
  • meiosis I
  • permeability

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • mitochondrial envelope
  • cellular membrane
  • Mitochondria
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc25a31 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • male meiosis I
  • cell differentiation
  • regulation of mitochondrial membrane permeability

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • motile cilium
  • mitochondrial permeability transition pore complex
  • membrane
  • mitochondrion
  • mitochondrial inner membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • ATP:ADP antiporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.