Phtf2 Gene Summary [Mouse]
Predicted to be located in endoplasmic reticulum. Is expressed in brain. Orthologous to human PHTF2 (putative homeodomain transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Phtf2 |
| Official Name | putative homeodomain transcription factor 2 [Source:MGI Symbol;Acc:MGI:1916020] |
| Ensembl ID | ENSMUSG00000039987 |
| Bio databases IDs | |
| Aliases | putative homeodomain transcription factor 2 |
| Synonyms | 1110054G21RIK, 9530062N20Rik, DKFZp564F013, putative homeodomain transcription factor 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Phtf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Homeodomain containing protein PHTF1/2, N-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypertension
- schizophrenia
- major depression
- cardioembolic stroke
regulated by
- dexamethasone
- TBX2
- mir-375 (includes others)
role in cell
- expression in
- proliferation
- colony formation
- migration
- sphere formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Phtf2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- endoplasmic reticulum