PHTF2 Gene Summary [Human]
Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PHTF2 |
| Official Name | putative homeodomain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:13411] |
| Ensembl ID | ENSG00000006576 |
| Bio databases IDs | |
| Aliases | putative homeodomain transcription factor 2 |
| Synonyms | 1110054G21RIK, 9530062N20Rik, DKFZp564F013, putative homeodomain transcription factor 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PHTF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Homeodomain containing protein PHTF1/2, N-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hypertension
- schizophrenia
- major depression
- cardioembolic stroke
regulated by
- dexamethasone
- TBX2
- mir-375 (includes others)
role in cell
- expression in
- proliferation
- colony formation
- migration
- sphere formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PHTF2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- endoplasmic reticulum