Gpr176 Gene Summary [Mouse]
Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and circadian behavior. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in brain and genitourinary system. Orthologous to human GPR176 (G protein-coupled receptor 176). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr176 |
| Official Name | G protein-coupled receptor 176 [Source:MGI Symbol;Acc:MGI:2685858] |
| Ensembl ID | ENSMUSG00000040133 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 176 |
| Synonyms | Gm1012, GPR, G protein-coupled receptor 176, HB-954, RBU-15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr176 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Gpr176 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- psoriasis
- breast cancer
- breast carcinoma
- diverticular disease
role in cell
- expression in
- proliferation
- apoptosis
- invasion by
- migration
- glycolysis in
- mitochondrial respiration in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr176 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
- G-protein coupled receptor signaling pathway
- synaptic transmission
- circadian behavior
Cellular Component
Where in the cell the gene product is active
- synapse
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity