Prrc2c Gene Summary [Mouse]
Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in cytosol. Is expressed in brain; cerebral cortex ventricular layer; cortical plate; lung; and main olfactory bulb. Orthologous to human PRRC2C (proline rich coiled-coil 2C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prrc2c |
| Official Name | proline-rich coiled-coil 2C [Source:MGI Symbol;Acc:MGI:1913754] |
| Ensembl ID | ENSMUSG00000040225 |
| Bio databases IDs | |
| Aliases | proline-rich coiled-coil 2C |
| Synonyms | 1810043M20RIK, 9630039I18Rik, A630006J20, Bat2d, BAT2D1, BAT2-iso, BAT2L2, E130112L15Rik, mKIAA1096, proline-rich coiled-coil 2C, Prrc3, RGD1566064, Similar to KIAA1096, XTP2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prrc2c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BAT2 N-terminus
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- uterine leiomyoma
- leiomyomatosis
- ocular sarcoidosis
- adenomyosis
- metabolic syndrome X
regulates
- mir-145
role in cell
- expression in
- growth
- assembly
- differentiation
- calcification
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prrc2c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- stress granule assembly
- hemopoietic progenitor cell differentiation
Cellular Component
Where in the cell the gene product is active
- cytoplasmic stress granule
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding