Cnrip1 Gene Summary [Mouse]
Predicted to enable type 1 cannabinoid receptor binding activity. Involved in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. Located in myelin sheath. Is active in GABA-ergic synapse; glutamatergic synapse; and presynapse. Is expressed in mesonephros. Orthologous to human CNRIP1 (cannabinoid receptor interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cnrip1 |
| Official Name | cannabinoid receptor interacting protein 1 [Source:MGI Symbol;Acc:MGI:1917505] |
| Ensembl ID | ENSMUSG00000044629 |
| Bio databases IDs | |
| Aliases | cannabinoid receptor interacting protein 1 |
| Synonyms | 1500041B16Rik, 3110054C06Rik, 5330437A18Rik, C2orf32, cannabinoid receptor interacting protein 1, CRIP-1, Crip1a, RGD1308373 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnrip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein-coupled receptor binding
- protein binding
- CB1 cannabinoid receptor-interacting protein 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- glutaminergic synapse
- Cytoplasm
- presynaptic regions
- Plasma Membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnrip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of receptor activity
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- type 1 cannabinoid receptor binding