Depp1 Gene Summary [Mouse]
Predicted to be involved in regulation of autophagy. Located in mitochondrion. Is expressed in endothelium of renal artery and metanephros. Orthologous to human DEPP1 (DEPP autophagy regulator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Depp1 |
| Official Name | DEPP1 autophagy regulator [Source:MGI Symbol;Acc:MGI:1918730] |
| Ensembl ID | ENSMUSG00000048489 |
| Bio databases IDs | |
| Aliases | DEPP1 autophagy regulator |
| Synonyms | 8430408G22Rik, C10orf10, DEPP, DEPP1 autophagy regulator, DEPP autophagy regulator 1, FIG, Fseg, X8430408G22Rik |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Depp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Decidual protein induced by progesterone family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- osteoarthritis
- organismal death
- endometriosis
- preeclampsia
- epileptic seizure
- systemic lupus erythematosus
role in cell
- apoptosis
- autophagy by
- cell viability
- autophagic flux in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Mitochondria
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Depp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- regulation of autophagy
Cellular Component
Where in the cell the gene product is active
- peroxisome
- cytoplasm
- intracellular membrane-bounded organelle
- mitochondrion