DEPP1 Gene Summary [Human]
The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]
Details
| Type | Processed Transcript |
| Official Symbol | DEPP1 |
| Official Name | DEPP1 autophagy regulator [Source:HGNC Symbol;Acc:HGNC:23355] |
| Ensembl ID | ENSG00000165507 |
| Bio databases IDs | |
| Aliases | DEPP1 autophagy regulator, decidual protein induced by progesterone, fasting induced, fat-specific expressed gene |
| Synonyms | 8430408G22Rik, C10orf10, DEPP, DEPP1 autophagy regulator, DEPP autophagy regulator 1, FIG, Fseg, X8430408G22Rik |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DEPP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Decidual protein induced by progesterone family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- osteoarthritis
- organismal death
- endometriosis
- preeclampsia
- epileptic seizure
- systemic lupus erythematosus
role in cell
- apoptosis
- autophagy by
- cell viability
- autophagic flux in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Mitochondria
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DEPP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- regulation of autophagy
Cellular Component
Where in the cell the gene product is active
- peroxisome
- cytoplasm
- intracellular membrane-bounded organelle
- mitochondrion