Prss50 Gene Summary [Mouse]
Predicted to enable threonine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Predicted to be active in endoplasmic reticulum. Is expressed in heart and pericardium and liver. Orthologous to human PRSS50 (serine protease 50). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prss50 |
| Official Name | protease, serine 50 [Source:MGI Symbol;Acc:MGI:2447303] |
| Ensembl ID | ENSMUSG00000048752 |
| Bio databases IDs | |
| Aliases | protease, serine 50 |
| Synonyms | 79H19C, CT20, RGD1309180, serine protease 50, TSP50 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss50 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- threonine endopeptidase
- peptidase
- Domain of unknown function (DUF1986)
Pathways
Biological processes and signaling networks where the Prss50 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- tumorigenesis
regulates
- D-glucose
- 2-phosphoglyceric acid
- glucose-6-phosphate
- PKM
- adenosine triphosphate
- lactic acid
- LDH (complex)
role in cell
- cell viability
- proliferation
- production in
- acidification
- acidification by
- acetylation in
- consumption in
- oxygen consumption in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss50 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase activity
- threonine-type endopeptidase activity