Ccnb3 Gene Summary [Mouse]
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be located in nuclear speck. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in germ cell of ovary; germ cell of testis; ovary; seminiferous tubule; and testis. Orthologous to human CCNB3 (cyclin B3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccnb3 |
| Official Name | cyclin B3 [Source:MGI Symbol;Acc:MGI:2183443] |
| Ensembl ID | ENSMUSG00000051592 |
| Bio databases IDs | |
| Aliases | cyclin B3 |
| Synonyms | AL671962.1, CYCB3, cyclin B3, RGD1564367 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccnb3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cyclin box
- Cyclin box fold superfamily
- Cyclin, N-terminal domain
- protein binding
- domain present in cyclins, TFIIB and Retinoblastoma
Pathways
Biological processes and signaling networks where the Ccnb3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- oocyte maturation defect
- susceptibility to recurrent pregnancy loss 1
role in cell
- degradation in
- formation
- formation in
- replication in
- cell cycle progression
- S phase
- metaphase I
- development
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccnb3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- meiotic cell cycle
- regulation of cyclin-dependent protein kinase activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- nuclear speck
- cyclin-dependent protein kinase holoenzyme complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- cyclin-dependent protein kinase regulator activity