Tlr11 Gene Summary [Mouse]
Predicted to enable signaling receptor activity. Acts upstream of or within response to bacterium. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tlr11 |
| Official Name | toll-like receptor 11 [Source:MGI Symbol;Acc:MGI:3045226] |
| Ensembl ID | ENSMUSG00000051969 |
| Bio databases IDs | |
| Aliases | toll-like receptor 11 |
| Synonyms | Gm287, RGD1564460, toll-like receptor 11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tlr11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
- protein binding
- Leucine Rich repeats (2 copies)
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Tlr11 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
- Altered T Cell and B Cell Signaling in Rheumatoid Arthritis
- Colorectal Cancer Metastasis Signaling
- Communication between Innate and Adaptive Immune Cells
- Neuroinflammation Signaling Pathway
- Parkinson's Signaling Pathway
- Phagosome Formation
- Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis
- Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses
- TREM1 Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- infection
- infection by bacteria
- infection by E. coli
phenotypes
- decreased circulating serum albumin level
role in cell
- expression in
- production in
- recruitment in
- recognition in
- recognition
- maturation
- response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane