Ubxn8 Gene Summary [Mouse]
Predicted to enable ubiquitin binding activity. Predicted to be involved in ERAD pathway. Predicted to be located in endoplasmic reticulum membrane; nucleolus; and nucleoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human UBXN8 (UBX domain protein 8). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ubxn8 |
| Official Name | UBX domain protein 8 [Source:MGI Symbol;Acc:MGI:1337129] |
| Ensembl ID | ENSMUSG00000052906 |
| Bio databases IDs | |
| Aliases | UBX domain protein 8 |
| Synonyms | D0H8S2298E, D8S2298E, REP8, Rep8h, RGD1306023, UBXD6, UBX domain protein 8 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ubxn8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNase H-like domain found in reverse transcriptase
- Ubl1_cv_Nsp3_N-like
- protein binding activity, bridging
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ubxn8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- single fertilization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nucleus
- ubiquitin ligase complex
- endoplasmic reticulum
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- ubiquitin binding
- protein binding, bridging