Prss2

Enables serine-type endopeptidase activity. Predicted to be involved in several processes, including collagen catabolic process; response to caffeine; and response to nicotine. Located in collagen-containing extracellular matrix. Is expressed in alimentary system; genitourinary system; and spleen. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to several human genes including PRSS1 (serine protease 1) and PRSS2 (serine protease 2). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Prss2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.