Idi1 Gene Summary [Mouse]
Predicted to enable isopentenyl-diphosphate delta-isomerase activity; magnesium ion binding activity; and manganese ion binding activity. Involved in response to stilbenoid. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human IDI1 (isopentenyl-diphosphate delta isomerase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Idi1 |
| Official Name | isopentenyl-diphosphate delta isomerase [Source:MGI Symbol;Acc:MGI:2442264] |
| Ensembl ID | ENSMUSG00000058258 |
| Bio databases IDs | |
| Aliases | isopentenyl-diphosphate delta isomerase |
| Synonyms | 4832416K17Rik, IDP ISOMERASE, IPP1, Ipp delta isomerase, IPPI1, IPP isomerase 1, Ipp δ isomerase, isopentenyl-diphosphate delta isomerase, isopentenyl-diphosphate delta isomerase 1, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl diphosphate isomerase, isopentenyl-diphosphate δ isomerase, isopentenyl-diphosphate δ isomerase 1, ISOPENTENYL PYROPHOSPHATE ISOMERASE, MGC8139, Similar to isopentenyl-diphosphate delta isomerase, Similar to isopentenyl-diphosphate δ isomerase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Idi1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- isopentenyl-diphosphate delta-isomerase, type 1
- NUDIX domain
- isopentenyl-diphosphate D-isomerase
- enzyme
- protein binding
- manganese ion binding
- magnesium ion binding
- NUDIX hydrolase superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- allergic rhinitis
- celiac disease
- colon carcinoma
- colon epithelial cancer
- experimental autoimmune encephalomyelitis
- atopic dermatitis
- pancreatic ductal adenocarcinoma
- pancreatic epithelial cancer
- ductal pancreatic cancer
regulates
- IDI1
- cholesterol
- lipid
- terpenoid
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Idi1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- isopentenyl diphosphate biosynthetic process
- dimethylallyl diphosphate biosynthetic process
- cholesterol biosynthetic process
Cellular Component
Where in the cell the gene product is active
- peroxisome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- isopentenyl-diphosphate delta-isomerase activity