Rpl10l Gene Summary [Mouse]

A structural constituent of ribosome. Involved in male meiosis I; ribosomal large subunit assembly; and spermatogenesis. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in spermatogenic failure 63. Orthologous to human RPL10L (ribosomal protein L10 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rpl10l
Official Name
ribosomal protein L10-like [Source:MGI Symbol;Acc:MGI:3647985]
Ensembl ID
ENSMUSG00000060499
Bio databases IDs NCBI: 238217 Ensembl: ENSMUSG00000060499
Aliases ribosomal protein L10-like
Synonyms EG238217, ribosomal protein L10-like, RPL10 5 1358, Rpl10l1, SPGF63
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl10l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • Ribosomal_L16_L10e
  • Ribosomal protein L16p/L10e

Pathways

Biological processes and signaling networks where the Rpl10l gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ulcerative colitis
  • spermatogenic failure 63
regulated by
regulates
  • Ribosomal Subunit 60s
role in cell
  • autophagy
  • autophagy in
  • meiosis I

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • ribosome
  • Endoplasmic Reticulum
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl10l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • male meiosis I
  • cell differentiation
  • ribosomal large subunit assembly
  • translation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • membrane
  • cytosol
  • endoplasmic reticulum
  • cytosolic large ribosomal subunit
  • ribosome

Molecular Function

What the gene product does at the molecular level
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.