Tor3a Gene Summary [Mouse]
Predicted to enable ATP hydrolysis activity. Located in endoplasmic reticulum lumen. Is expressed in lateral ventricle choroid plexus and pancreas tip epithelium. Orthologous to human TOR3A (torsin family 3 member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Tor3a |
| Official Name | torsin family 3, member A [Source:MGI Symbol;Acc:MGI:1353652] |
| Ensembl ID | ENSMUSG00000060519 |
| Bio databases IDs | |
| Aliases | torsin family 3, member A |
| Synonyms | ADIR, ADIR2, ATP-dependent interferon responsive, torsin family 3 member A, torsin family 3, member A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tor3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Torsin
- enzyme
- protein binding
- ATPase
- P-loop containing Nucleoside Triphosphate Hydrolases
- ATPases associated with a variety of cellular activities
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- endoplasmic reticulum lumen
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tor3a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- endoplasmic reticulum lumen
- extracellular vesicular exosome
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding