Pi15 Gene Summary [Mouse]
Predicted to enable peptidase inhibitor activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in glomerular tuft; renal cortex; s-shaped body; visceral epithelium of capillary loop renal corpuscle; and visceral epithelium of mature renal corpuscle. Orthologous to human PI15 (peptidase inhibitor 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pi15 |
| Official Name | peptidase inhibitor 15 [Source:MGI Symbol;Acc:MGI:1934659] |
| Ensembl ID | ENSMUSG00000067780 |
| Bio databases IDs | |
| Aliases | peptidase inhibitor 15 |
| Synonyms | CRISP8, P24TI, P25TI, peptidase inhibitor 15, SugarCrisp |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pi15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains
- CAP
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pi15 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- peptidase inhibitor activity